Dr. Giulia ADRIANI

Academic qualifications

2012: Ph.D. in Biomedical and Biomechanical Engineering – Interpolythechnic Doctorate School Polytechnic of Bari, Italy
2008: M.S. with honors in Mechanical Engineering -Polytechnic of Bari, Italy
2006: B.S. with honors in Mechanical Engineering -Polytechnic of Bari, Italy

Professional experience

• Principal Investigator. SIgN, A*STAR, Singapore. 2019 – present
• Adjunct Assistant Professor. NUS, Singapore. 2019 – present
• Research Scientist. SMART, Singapore. 2016 – 2018
• Postdoctoral Associate. SMART, Singapore. 2013 – 2015
• Research Fellow. NUS, Singapore 2012-2013
• Visiting student. Houston Methodist Research Institute, Houston, TX, USA. 2010-2011

Research Interest

1. Organ-on-a-chip models
2. Immunology and Immunotherapy
3. Cancer biology and cancer therapy
4. Nanoparticle for drug delivery

Selected Awards & Honours

• 2018 Best Poster Award at the 11th European and Global Summit for Clinical Nanomedicine, Targeted Delivery and Precision Medicine
• 2016 AACR-­Bristol-­Myers Squibb Oncology Scholar-­in-­Training Award
• 2016 CREATE Global Connector Program -­ MIT and EmTech
• 2016 Best Poster Award at the 8th International Singapore Symposium of Immunology
• 2010 PhD Fellowship Interpolytechnic Doctorate School

Membership in Scientific/Professional Organization

• Singaporean  Society  for  Immunology (SgSI)
• IEEE Engineering in Medicine and Biology Society (EMBS)
• European Academy for Tumor Immunology (EATI)

Selected Journal Publications

1. Mercurio A, Sharples L, Corbo F, Franchini C, Vacca A, Catalano A, Carocci A, Kamm RD, Pavesi A, Adriani G. Phthalimide Derivative Shows Anti-Angiogenic Activity in a 3D Microfluidic Model and no Teratogenicity in Zebrafish Embryos. Front. Pharmacol. 2019;10:1472–12.
2. Bersini S, Miermont A, Pavesi A, Kamm RD, Thiery JP, Moretti M, Adriani G. A combined microfluidic-­ transcriptomic approach to characterize the extravasation potential of cancer cells. Oncotarget 2018;9:36110-­36125.
3. Yuan Y, Adriani G, Xu Y, Chan YT. Highly fluorescent, monolithic semiconductor nanorod clusters for ultrasensitive  biodetection.  ChemComm.  2018;54(80):11352-‑11355.
4. Lee SWL, Adriani G, Ceccarello E, Pavesi A, Tan AT, Bertoletti A, Kamm RD, Wong SC. Characterizing the  Role  of  Monocytes  in  T  Cell  Cancer  Immunotherapy  Using  a  3D  Microfluidic  Model. Front. Immunol. 2018 9:416.
5. Adriani G, Ma D, Pavesi A, Kamm RD, Goh ELK. A 3D neurovascular microfluidic model consisting of neurons,  astrocytes  and  cerebral  endothelial  cells  as  a  blood-­brain  barrier.  Lab  Chip.  2017;17(3):448-­459.
6. Pavesi  A,  Tan  AT,  Koh  S,  Chia  A,  Colombo  M,  Antonecchia  E,  Miccolis  C,  Ceccarello  E,  Adriani  G,  Raimondi MT, Kamm RD, Bertoletti A. A 3D microfluidic model for preclinical evaluation of TCR-­ engineered T cells against solid tumors. JCI Insight. 2017;2(12):e89762.
7. Ho  YT,  Adriani  G,  Beyer  S,  Nhan  PT,  Kamm  RD,  Kah  JCY.  A  Facile  Method to  Probe  the  Vascular  Permeability of Nanoparticles in Nanomedicine Applications. Sci Rep. 2017;7(1):707.
8. Adriani G, Pavesi A, Tan AT, Bertoletti A, Thiery JP, Kamm RD. Microfluidic models for adoptive cell-­ mediated cancer immunotherapies. Drug Discovery Today. 2016;21(9):1472-­1478.
9. Penny HL, Sieow JL, Adriani G, Yeap WH, Ee PSC, San Luis B,  Lee B, Lee T, Mak SY, Ho YS, Ong CK, Huang RYJ, Ginhoux F, Rotzschke O, Kamm RD, Wong SC. Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma. Oncoimmunology.2016;5(8):e1191731.