Dr. Dean HO

Head, Department of Biomedical Engineering

Provost’s Chair Professor

Director, The N.1 Institute for Health (N.1), Director, The Institute for Digital Medicine (WisDM)

Education

  • PhD. in Biomedical Engineering. UCLA. 2005.
  • MSc. in Biomedical Engineering. UCLA. 2003.
  • BSc. in Physiological Sciences. UCLA. 2001.

Professional Experience

  • Professor. NUS. 2018.
  • Co-Director. The Jane and Jerry Weintraub Center for Reconstructive Biotechnology, UCLA. 2012.
  • Professor. UCLA. 2012.
  • Assistant Professor. Northwestern University. 2006 – 2010.
  • Research Associate. Caltech California Nanosystems Institute/Hewlett-Packard Postdoc, UCLA. 2005 – 2006.

Research Interest

  1. Personalized medicine technologies
  2. Development of nanodiamond platforms for drug delivery

Technopreneurship & Startups

  1. Co-Founder, KYAN Therapeutics, Inc
  2. Co-Founder, Biotic Laboratories, Inc

Selected Awards & Honours

  1. Elected to the US National Academy of Inventors, 2018
  2. Fulbright Scholar, Core US Scholar Program, US Department of State, 2017
  3. Fellow, Society for Laboratory Automation and Screening, 2016
  4. Fellow, American Institute for Medical and Biological Engineering, 2015
  5. William J. Gies Award, International Association for Dental Research, 2015
  6. President, Board of Directors, Society for Laboratory Automation and Screening, 2015
  7. Top 10 Innovator, Journal of Laboratory Automation, 2015
  8. Coulter Fellow, Wallace H. Coulter Foundation, 2014
  9. Young Investigator Award, International Association for Dental Research, 2014

Membership in Scientific/Professional Organization

  • Materials Research Society
  • Member, Biomedical Engineering Society
  • Full Member, Sigma Xi Research Society (Elected)
  • International Association of Dental Research (IADR)

Selected Journal Publications

  1. D. Ho, P. Wang, and T. Kee, Artificial Intelligence in Nanomedicine, Nanoscale Horizons, DOI:10.1039/C8NH00233A, 2019, Cover Article (Back).
  2. Pantuck, D.K. Lee, T. Kee, P. Wang, S. Lakhotia, M. Silverman, C. Mathis, A. Drakaki, A.S. Belldegrun, C.M. Ho, and D. Ho, Modulating BET Bromodomain Inhibitor ZEN‐3694 and Enzalutamide Combination Dosing in a Metastatic Prostate Cancer Patient Using CURATE.AI, an Artificial Intelligence Platform, Advanced Therapeutics, DOI: 10.1002/adtp.201800104, 2018, Cover Article.
  3. Rashid M, Toh TB, Hooi L, Silva A, Zhang Y, Tan PF, The AL, Karnani N, Jha S, Ho CM, Chng WJ, Ho D, Chow EK; Optimizing drug combinations against multiple myeloma using a quadratic phenotypic optimization platform (QPOP); Science Translational Medicine, 2018 Aug 8;10(453).
  4. C. Hong, D. Song, D.K. Lee, L. Lin, H.C. Pan, D. Lee, P. Deng, Z. Liu, D. Hadaya, A. Mohammad, X. Zhang, M. Lee, C.Y. Wang, and D. Ho, Reducing Post-Treatment Relapse in Cleft Lip Palatal Expansion Using an Injectable Estrogen-Nanodiamond Hydrogel, Proceedings of the National Academy of Sciences of the United States of America, Early Edition (Week of August 14, 2017), 2017.
  5. Zarrinpar, A.; Lee, D.-K.; Silva, A.; Datta, N.; Kee, T.; Eriksen, C.; Weigle, K.; Agopian, V.; Kaldas, F.; Farmer, D.; Wang, S. E.; Busuttil, R.; Ho, C.-M.; Ho, D., Individualizing liver transplant immunosuppression using a phenotypic personalized medicine platform. Science Translational Medicine 2016, 8 (333), 333ra49-333ra49. Cover Article
  6. Laura Moore, Junyu Yang, Thanh T. Ha Lan, Eiji Osawa, Dong-Keun Lee, William D. Johnson, Jianzhong Xi, Edward Kai-Hua Chow, and Dean Ho, Biocompatibility Assessment of Detonation Nanodiamond in Non-Human Primates and Rats Using Histological, Hematologic, and Urine Analysis, ACS Nano 2016 10 (8), 7385-7400.
  7. Dean Ho*, Katherine Chung-Huei Wang, and Edward Chow, Nanodiamonds: The Intersection of Nanotechnology, Drug Development, and Personalized Medicine, Science Advances, e1500439, 2015.
  8. Hann Wang, Dong-Keun Lee, Kai-Yu Chen, Jing-Yao Chen, Kangyi Zhang, Aleidy Silva, Chih-Ming Ho, and Dean Ho*, Mechanism-Independent Optimization of Combinatorial Nanodiamond and Unmodified Drug Delivery Using a Phenotypically Driven Platform Technology, ACS Nano, 2015, 9 (3), 3332-3344, Featured in over 20 international news outlets.
  9. Xin Wang, Xinyi Casuarine Low, Weixin Hou, Lissa Nurrul Abdullah, Tan Boon Toh, Masturah Mohd Abdul Rashid, Dean Ho, and Edward Kai-Hua Chow, Epirubicin-Adsorbed Nanodiamonds Kill Chemoresistant Hepatic Cancer Stem Cells, ACS Nano, 2014, 8 (12), 12151-12166, Featured in Straits Times, Channel News Asia, and over 30 international news outlets.
  10. Samir Mitragotri, Daniel G. Anderson, Xiaoyuan Chen, Edward K. Chow, Dean Ho, Alexander V. Kabanov, Jeffrey M. Karp, Kazunori Kataoka, Chad A. Mirkin, Sarah Hurst Petrosko, Jinjun Shi, Molly M. Stevens, Shouheng Sun, Sweehin Teoh, Subbu S. Venkatraman, Younan Xia, Shutao Wang, Zhen Gu, and Chenjie Xu, Accelerating the Translation of Nanomaterials in Biomedicine, ACS Nano, 2015, Article ASAP, DOI: 10.1021/acsnano.5b03569