Research Interest
Basic and applied research on Medical Instrumentation, Micro and Nanotechnology and Signal Processing with focus on Neuroengineering.
Mission:
- To sustain an internationally recognized basic research program on basic and clinical neuroscience research on the mechanism and therapy of brain diseases and disorders.
- To develop a nationally recognized program for technology development and commercialization of medical instrumentation and technology with a focus on Neuroengineering.
- Develop innovative micro and nanotechnologies and prosthetic devices for medical research and clinical applications, especially in the area of neurosciences.
- To develop economic medical and health care technology for global health. To develop innovative technologies and promote their commercialization through University-industry partnerships and spinoffs
- To educate students and post-doctoral scientists for careers in academia and industry and to foster a vibrant academic-industry relationship.
- To create an innovative educational frame-work through innovative new curricula, emphasis on design in undergraduate curriculum, and to provide professional/continuing training
- Publications, presentations, and organizational leadership at national and international conferences and symposia.
- To foster research collaboration and education at the international level.
Professional Activities
- Award Committee: Provost Award, 1998-present; Johns Hopkins University
- Editorial Advisory Board, IEEE T-BME (2002-present)
- Director, Neuroengineering Training Program, Johns Hopkins University (2004-present); Member Provost Research Award committee, chair or member of ad hoc promotion committees, member Whiting School of Engineering international program and collaboration group.
- Biomedical Microdevices and Nanotechnology (2008-present)
- Editorial Board, Frontiers of Neuroengineering (2009-present)
- International Journal of Neural Systems and Engineering (2010-present)
- Scientific Advisory Board, 2012
Book
- Quantitative EEG Analysis Methods and Clinical Applications, S. Tong and N. V. Thakor (Eds)., Artech House, Boston, MA, 2009.
Selected Journal Publications
- Fifer M. S., Acharya S., Benz H. L., Mollazadeh M., Crone N. E., Thakor N. V. Toward Electrocorticographic Control of a Dexterous Upper Limb Prosthesis: Building Brain-Machine Interfaces, IEEE Pulse, Vol. 3(1), pp. 38-42, Jan 2012.
- Andersen R. A., Schieber M. H., Thakor N. V., Loeb G. E. Natural and Accelerated Recovery from Brain Damage: Experimental and Theoretical Approaches IEEE Pulse, pp 61-65, Mar 2012
- Bazley F. A., Hu C., Maybhate A., Pourmorteza A., Pashai N., Thakor N. V., Kerr C., All A. H. “Electrophysiologal evaluation of sensory and motor pathways after incomplete unilateral spinal cord contusion”. J. Neurosurgery: Spine, 03 Feb 2012.
- Rege A., Thakor N. V., Rhie K., and Pathak A. P., In vivo laser speckle contrast imaging reveals microvascular remodeling and hemodynamic changes during wound healing angiogenesis, Angiogenesis, Vol. 15(1), pp. 87-98, 2012. PMID: 22198198.
- Rege A., Murari K., Seifert A., Thakor N. V., Multiexposure laser speckle contrast imaging of the angiogenic environment, J. Biomed. Optics, Vol. 16(5): pp. 601-610, 2012. PMCID: 3124539.
- Lalitha A., Thakor N. V. Design of an Accelerometer-Controlled Myoelectric Human Computer Interface Advanced Materials Research, Vol. 403, pp. 3973-3979, 09 Feb 2012.
- Wu D., Xiong W., Jia X., Geocadin R., Thakor N. V. Short-and long-latency somatosensory neuronal responses reveal selective brain injury and effect of hypothermia in global hypoxic ischemia Am Physiol Soc, Vol. 107(4), pp 1164-1171,15 Feb 2012.
- Kim H., Kim Y., Shin H., Aggarwal V., Schieber M. H., Thakor N. V. Neuron selection by relative importance for neural decoding of dexterous finger prosthesis control application Biomed Signal Proc Control, 02 Apr 2012.
- Thakor N. V. Highlights: Transcranial imaging of functional cerebral hemodynamic changes in single blood vessels J. Cerebral Blood Flow Metabolism, 04 Apr 2012
- Yang I. H. Gary D., Malone M., Dria S., Houdayer T., Belegu V., Mcdonalod J., and Thakor N. V., Axon myelination and electrical stimulation in a microfluidic, compartmentalized cell culture platform, Nanomolecular Medicine, 13 Apr 2012.
- Hosmane S., Tegenge M. A., Rajbhandari L., Uapinyoying P., Kumar N. G., Thakor N. V., Venkatesan A. Toll/Interleukin-1 Receptor Domain-Containing Adapter Inducing Interferon-β Mediates Microglial Phagocytosis of Degenerating Axons J. Neuroscience, 32(22), pp. 7745-7757, 30 May 2012.
- Saxena S., Schieber M. H., Thakor N. V., and Sarma S. V., Aggregate input output models of neuronal populations, IEEE Trans. Biomed. Eng., pp. 2030-2039, Jul 2012.
- Zhang H., Benz H. L., Thakor N. V., and Bezerianos A., Connectivity mapping of human brain by phase-based evolution map approach, Int. J. Bifurc. Chaos, Vol. 22 (9), 2012. doi: 1142/S0218127412502252, http://dx.doi.org/10.1142/S0218127412502252.
- Rege A*, Senarathna J*, Li N, Thakor N. V., Anisotropic processing of laser speckle images improves spatiotemporal resolution, IEEE Trans Biomed Engr vol. 59, no. 5, pp. 1272-128, 2012. (*equal contributions).
- Rege A., Thakor N. V., and Pathak A. P., Optical imaging of microvascular morphology and perfusion, Current Angiogenesis, Vol. 1, pp. 243-260, 2012.
- Boustany N. and Thakor N. V., Light scatter spectroscopy and imaging of cellular and subcellular events, CRC Handbook of Biophotonics, T. Vo-Dinh (Ed), 2nd Ed., 2012.
- Madhok J., Wu D., Xiong W., Geocadin R. G., Jia X., Hypothermia amplifies somatosensory evoked potentials in uninjured rats, J. Neurosurg. Anesthesiol. Vol. 24, no. 3, pp. 197-202, 2012.
- Kortelainen J, Jia X, Seppänen T, Thakor NV. Increased Electroencephalographic Gamma Activity Reveals Awakening from Isoflurane Anaesthesia in Rats. British Journal of Anaesthesia, In Press, 2012.
- Nag S., Jia X., Thakor N. V., Sharma D. Flexible Charge Balanced Stimulator with 5.6 fC Accuracy for 140 nC Injections, IEEE Trans. Biomedical Circuits Systems, In Press, 2012
- Santaniello S., Sherman D. L, Thakor N. V., Eskandar E. N., and Sarma S. V., Optimal control-based Bayesian detection of Clinical and behavioural state transitions, IEEE Trans. Neural Systems Rehab. Eng., Accepted, 2012.
- Yuan-Jen Chang, Lun-De Liao, Chin-Teng Lin, Hsin-Yi Lai, Ji-Lin Chen, Yu-Ting Yang, Ying-Chen Ting, Ya-Po Huang, Robby Wu, Nitish V. Thakor and You-Yin Chen, “A low-cost multi-electrode array system for the simultaneous acquisition of electrophysiological signal and cellular morphology,” Accepted, Journal of Neuroscience and Neuroengineering, 2012.